Beyonce with her friends John Legend, Jennifer Lopez and Madonna performed in support of Chime for Change, a campaign set up to help empower girls and women around the world.
Beyonce is co-founder, with actress-producer Salma Hayek Pinault and Gucci creative director Frida Giannini, of the charity, which supports projects improving access to education, health care and justice for women.
Beyonce performed "Crazy In Love" – joined onstage by husband Jay-Z. She also performed hits including "Single Ladies (Put A Ring On It)," "Run The World (Girls)," "Halo" and the Destiny's Child classic "Survivor."
Earlier, Simon Le Bon performed with Timbaland, and J-Lo and Mary J. Blige sang The Beatles' "Come Together," as a raft of stars united for the Sound of Change Live show, which also featured John Legend, Florence + The Machine and Rita Ora.
Madonna, Freida Pinto, Aishwarya Rai, Jada Pinkett Smith, James Franco, Ryan Reynolds, Jessica Chastain and feminist icon Gloria Steinem were among the presenters. Even Prince Harry sent a videotaped message of support.